The University of Latvia (Latvijas Universitāte) in Riga is the country's oldest and largest university (founded 1919), offering a six-year English-taught medical programme through its Faculty of Medicine. Clinical training takes place at Pauls Stradiņš Clinical University Hospital, Riga East Clinical University Hospital, and the Latvian Centre of Infectious Diseases — collectively providing comprehensive clinical exposure across all major specialties. The University of Latvia's programme is smaller than RSU's, offering a more intimate student experience with approximately 80-100 international students per cohort.

Research strengths include molecular biology, virology, pharmacology, and medical genetics — the Latvian Biomedical Research and Study Centre is closely affiliated. The university also benefits from strong links with the Latvian Institute of Organic Synthesis, a world-renowned chemistry research centre that has produced significant pharmaceutical discoveries. Riga provides an outstanding student experience with its UNESCO-listed old town, vibrant cultural calendar, coastal proximity, and affordable living.

For UK students, the University of Latvia offers a slightly smaller, more personal alternative to RSU with the same EU-recognised qualifications and GMC registration pathway.